Two strangers, freelance photographer Adam Stanheight and Dr. Lawrence Gordon, awaken in a dilapidated bathroom with no memory of how they ended up there. Both men find a tape recording each in their pockets, and not long after listening to them, realize they have been trapped in a "game" perpetrated by the infamous Jigsaw Killer. Escape seems unlikely at first, but Adam and Lawrence soon realize they may have a chance. But at what cost? And are they alone?